Clinical depression is classified as a type of mental illness, rather than a temporary emotional stage caused by life events such as grieving. Causes of clinical depression can be linked to any combination of biological, psychological, and social sources of stress. These combined factors may alter the activities of neural brain circuits and manifest themselves in both physical and psychological changes.

A person may experience a loss of interest in activities that they once enjoyed, with no seemingly way to counter the effects of sadness. There are several life events which can also lead to clinical depression:

1. Family issues
Family dynamics is a known trigger for depression. The relationships between parents and siblings, or parents and children are key indicators of whether someone may fall into a depressed state. The relationship between partners or spouses also plays a role in mental health.

2. Financial strain
Research has indicated a clear connection between financial health and mental health. This link has been found to be cyclical in nature, meaning that poor mental health often led to poor financial health, which then led to even poorer mental health thus perpetuating the cycle. Additionally, those who have perceived financial strain are nearly three times as likely to suffer from mental health issues including depression than those who are financially stable.

3. Social exclusion
Oftentimes social exclusion can be used as a risk avoidance mechanism for those who want to keep from suffering from their social circle, and is a key indication that someone may be suffering from depression. There is said to be a correlation between ostracism and the development of psychological disorders like depression, along with the negative social stigma attached to depression and social avoidance. Whether to ostracism is self-imposed due to personal conflict, or an event of outside factors, this state of being is not a healthy way of being to maintain psychological development.

4. Death or loss
Going through the stages of grief after the death of a loved one (person or pet) is normal, and seen as a healthy coping mechanism. There are several key differences between the typical stages of grief and the longstanding suffering of clinical depression because of loss. Some differences include the duration of grief, acceptance of support, and ability to function. Those who are clinically depressed often isolate themselves and refuse to accept outside support. Their grief also may become a permanent state and can impact their daily lives, making it difficult to complete normal tasks.

5. Divorce or breakup
The adjustment that one must go through after a divorce or breakup can lead to depression. The separation is often a major life change that may be completely out of one’s control and not the outcome that was desired. When this adjustment period is prolonged without end, it can then lead to clinical depression. Some symptoms include ignoring responsibilities and avoiding social groups. The risk is increased two-fold if a person already has symptoms of depression before the separation.

6. Personal trauma
Traumatic experiences can have long-lasting effects leading to emotional and psychological trauma. Initial reactions of anxiety, dissociation, confusion, and sadness are considered normal and are usually self-limited. When these reactions persist, however, is when it may be necessary to seek professional treatment for clinical depression. Outside of professional treatment, it is also recommended that sufferers try to participate in activities that they enjoy and spend time with friends and family.

If any of these symptoms seem familiar, there are many resources to seek professional help.